Applications for

Pluripotent Stem Cells (PSCs)

vertical-wheel based bioreactors

Aggregate Perfusion Medium Exchange in Vertical-Wheel Bioreactors for Scalable PSC Production

Linear Scale-up of hiPSC Cell Lines Using Vertical-Wheel Bioreactors

Superior Microcarrier-Based iPSC Expansion in PBS-3 VW Bioreactor

The Use of Vertical-Wheel Technology for Superior Culture Homogeneity and Expansion of hiPSCs

Overcoming Scale-Up Challenges in iPSC Production: A joint investigation by PBS Biotech and Carr Biosystems

Addressing Bioreactor hiPSC Aggregate Stability, Maintenance and Scaleup Challenges Using a Design of Experiment Approach

Complete Suspension Differentiation of Human Pluripotent Stem Cells into Pancreatic Islets Using Vertical-Wheel Bioreactors

Extracellular Vesicle Biogenesis of Three-dimensional Human Pluripotent Stem Cells in a Novel Vertical-Wheel Bioreactor

Measurement of Oxygen Transfer Rate and Specific Oxygen Uptake Rate of h-iPSC Aggregates in Vertical Wheel Bioreactors to Predict Maximum Cell Density Before Oxygen Limitation

Optimized Serial Expansion of Human Induced Pluripotent Stem Cells Using Low-Density Inoculation to Generate Clinically Relevant Quantities in Vertical-Wheel Bioreactors

Profiling Biomanufactured Extracellular Vesicles of Human Forebrain Spheroids in a Vertical-Wheel Bioreactor

Robust Bioprocess Design and Evaluation of Commercial Media for the Serial Expansion of Human Induced Pluripotent Stem Cell Aggregate Cultures in Vertical-Wheel Bioreactors

Scalable Bioreactor-based Suspension Approach to Generate Stem Cell–derived Islets From Healthy Donor-derived iPSCs

Scalable Culture of Human Induced Pluripotent Cells on Microcarriers Under Xeno-Free conditions Using Single-Use Vertical-Wheel Bioreactors

Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining

Scale up Manufacturing Approach for Production of Human Induced Pluripotent Stem Cell-derived Islets using Vertical-Wheel Bioreactors

Strategies for the Expansion of Human Induced Pluripotent Stem Cells as Aggregates in Single-use Vertical-Wheel Bioreactors

Suspension Culture Improves iPSC Expansion and Pluripotency Phenotype

Transcriptome Profiling of Human Pluripotent Stem Cell‐derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions

Perfusion Feed and External Oxygenation Utilized to Achieve Linear Scale-Up of iPSC Culture into 80L Vertical-Wheel Bioreactor

Producing T Cell Competent Blood Progenitor Cells From Pluripotent Stem Cells in Scalable Dynamic Suspension Culture

Key Requirements for Efficient and Linear Scale-Up of Shear Sensitive Pluripotent Stem Cell and Other Cell Therapy Products Using the Vertical-Wheel Bioreactor Family

Scalable Manufacturing of Human Mesenchymal Stem/Stromal Cells And Induced Pluripotent Stem Cells In Vertical-Wheel Bioreactors

Linear Scale-up of hiPSC Cell Lines Using Vertical-Wheel Bioreactors

Protocol Development to Overcome Bioprocess Bottlenecks in the Large-Scale Expansion of High Quality hiPSC Aggregates in Vertical-Wheel Bioreactors

Computational Fluid Dynamic Characterization of Vertical-Wheel Bioreactors For Effective Scale-Up of Human Induced Pluripotent Stem Cell Aggregate Culture

Expansion of PSC Aggregates in the PBS-Mini Vertical-Wheel Bioreactor

Video Guide to PSC Aggregate Culture Optimization

Scalable PSC and Donor-Derived Immune Cell Expansion Using the Vertical-Wheel Bioreactor Platform