PBS-3 Vertical Wheel Bioreactors

 PBS-15 Vertical-Wheel Bioreactor

The PBS-15 Vertical-Wheel bioreactor is the next step in scaling up the cell culture process started in the PBS-Minis and PBS-3. With a maximum working volume of 15L, the PBS-15 can accommodate larger scale process development or production for clinical trials.

  • Continue scale up of process development or clinical stage production
  • Configurations available for use with single-use or reusable DO and pH sensors
  • Adjustable height harvest valve (AHHV) allows for rapid medium exchange, sampling, and harvesting
  • Touchscreen interface for intuitive process customization, control, and reporting
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PBS-15 Vertical-Wheel Bioreactor Resources

Part Numbers
Specifications
Application Notes
Manuals
Product Type Product Name Product Number
Bioreactors PBS-15 Vertical-Wheel Bioreactor (120 V) IA-15-B-501
PBS-15 Vertical-Wheel Bioreactor (240 V) IA-15-B-502
PBS-15 Vertical-Wheel Bioreactors, Single-Use Sensors (120 & 240 V) IA-15-B-701
Single-Use Vessels PBS-15 Vertical-Wheel Single-Use Vessel (Floored Wheel) IA-15-D-504-L
PBS-15 Vertical-Wheel Single-Use Vessel (Floorless Wheel) IA-15-D-506-L
PBS-15 Vertical-Wheel Single-Use Vessels, Single-Use Sensors (Floored Wheel) IA-15-D-704-L
Accessories PBS Autoclavable Probe Connector IA-UNI-DA-001
Reusable DO Sensor, 12mm OD x 220mm L with Right-Angle IC00468
Reusable pH Sensor, 12mm OD x 225mm L IC00469
Software PBS-15 Vertical-Wheel Bioreactor Software 3.0 (21 CFR Part 11 cGMP Upgrade) IA-15-SW-001
Qualification Packages PBS-15 Vertical-Wheel Bioreactor IQ/OQ Protocols IA-15-BQ-004
PBS-15 Vertical-Wheel Bioreactor IQ/OQ Configuration Sheet IA-15-BQ-005
Working volume range: 9 – 15 L
Gas control Mass flow controllers for air, N2, O2, CO2
Vessel construction Polyvinylidene Fluoride (PVDF)
Product contact materials Meet requirements for USP Class VI Testing for Plastics <88> and/or ISO 10993
Download Full  Technical Spec Sheet
Application Note Title  
Defined Biomatrices Accelerate MSC Manufacturing Across Scales Read Now
Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors Read Now
Title  
PBS-15 and PBS-80 Single-Use Bioreactors User Manual (Software v3) [P/Ns: IA-15-B-501 & -502; IA-80-B-511 & -512] Read Now
PBS-15 Datasheet Read Now
PBS-Mini Single-use bioreactor in the lab

 Need Help Maximizing the Yield and Quality of Your Cells?

We can help! Our team of scientists and engineers are well-versed in developing cell culture procedures for various types of therapeutic cells using the PBS-15 single use bioreactor. We can help with:

  • Cell separation, washing, and concentration
  • Rapid medium exchange techniques
  • Aggregate-based processes including seeding, expansion, differentiation, dissociation, and harvesting
Request Support Now