Your Scale-up Partner
Vertical-Wheel® Technology is a proprietary, purpose built platform specifically designed for cell therapy development and linear scale-up. Advance your process smoothly from initial data generation to commercial scale-up with confidence.
and Make Your Process Scale-proof
PBS Biotech provides a complete cell therapy manufacturing solution: scalable bioreactor systems, a controlled cell growth environment, and the support to make scaling your process predictable.
A Paradigm Shift from Stirred Tank Bioreactors
Energy spreads evenly across the whole vessel. There are no high- or low-shear zones and none of the turbulent bands a stirred tank impeller produces.
A scalable impeller-to-vessel ratio keeps the mixing environment identical as vessels grow, all the way to commercial volumes.
Homogeneous EDR gives predictable control over aggregate size, and the same mechanical energy can dissociate aggregates directly in the vessel.
One Platform, Five Scales
From 60mL to 80L, each system shares the same Vertical-Wheel® Technology - ensuring linear scalability of the same gentle cell growth environment and allowing our world-class support to help drive your programs from the lab to the clinic to commercial launch.
Optimize your Process
Find examples of published runs, seeding densities, and scale-up data, organized by cell types.
