Publications
2025 Kim et al.
Measurement of Oxygen Transfer Rate and Specific Oxygen Uptake Rate of h-iPSC Aggregates in Vertical Wheel Bioreactors to Predict Maximum Cell Density Before Oxygen Limitation
2025 Verhoeff, MD et al.
Scalable Bioreactor-based Suspension Approach to Generate Stem Cell–derived Islets From Healthy Donor-derived iPSCs
2024 Muok et al.
Extracellular vesicle biogenesis of three-dimensional human pluripotent stem cells in a novel Vertical-Wheel bioreactor
2024 Liu et al.
Profiling biomanufactured extracellular vesicles of human forebrain spheroids in a Vertical-Wheel Bioreactor
2024 Borys et al.
Robust bioprocess design and evaluation of commercial media for the serial expansion of human induced pluripotent stem cell aggregate cultures in vertical-wheel bioreactors
2024 Yehya et al.
Addressing Bioreactor hiPSC Aggregate Stability, Maintenance and Scaleup Challenges Using a Design of Experiment Approach
2024 Jeske et al.
Upscaling Human Mesenchymal Stromal Cell Production in a Novel Vertical-Wheel Bioreactor Enhances Extracellular Vesicle Secretion and Cargo Profile
2024 Iworma et al.
Metabolic Switching, Growth Kinetics and Cell Yields in the Scalable Manufacture of Stem Cell‑Derived Insulin‑Producing Cells
2023 Vallabhaneni et al.
Suspension Culture on Microcarriers and as Aggregates Enables Expansion and Differentiation of Pluripotent Stem Cells
2023 Roberts et al.
Computer Controlled Expansion of Equine Cord Blood MSCs on Microcarriers in 3L Vertical-Wheel Bioreactors
2023 Roberts et al.
Bioprocess Development for Cord Blood Mesenchymal Stromal Cells on Microcarriers in Vertical‐Wheel Bioreactors
2023 Cuesta-Gomez et al.
Suspension Culture Improves iPSC Expansion and Pluripotency Phenotype
2022 Arthur et al.
Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid‑Derived Exosomes
2022 Neto et al.
Characterization of the Aeration and Hydrodynamics in Vertical-Wheel Bioreactors
2022 Lee et al.
Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products
2022 Croughan et al.
Initial Power Measurements for a Family of Novel Vertical-Wheel Bioreactors
2021 Silva et al.
Transcriptome Profiling of Human Pluripotent Stem Cell‐Derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions
2021 Dang et al.
Computational Fluid Dynamic Characterization of Vertical-Wheel Bioreactors Used for Effective Scale-up of Human Induced Pluripotent Stem Cell Aggregate Culture
2021 Borys et al.
Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors
2020 Silva et al.
Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining
2020 Lee et al.
Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products
2020 Borys et al.
Optimized Serial Expansion of Human Induced Pluripotent Stem Cells Using Low-Density Inoculation to Generate Clinically Relevant Quantities in Vertical-Wheel Bioreactors
2019 Nogueria et al.
Strategies for the Expansion of hiPSCs as Aggregates in Single-Use Vertical-Wheel Bioreactors
2018 Rodrigues et al.
Scalable Culture of Human Induced Pluripotent Cells on Microcarriers Under Xeno-Free conditions Using Single-Use Vertical-Wheel Bioreactors
2018 Jung et al.
Quality Manufacturing of Mesenchymal Stem/Stromal Cells Using Scalable and Controllable Bioreactor Platforms