Defined Biomatrices Accelerate MSC Manufacturing Across Scales
Introduction
Cell-based therapies are promising medical treatments for a broad range of diseases. Predominantly, stem cells are utilized for those treatments, which are sourced either patient-specific for autologous therapies or from healthy donors as part of allogeneic therapies. The advantage of an allogeneic approach is the possibility to expand cells to clinically relevant numbers independent of the patient's medical state, therapy time point, and location. Moreover, the establishment of stem cell banks comprising different donors allows for timely therapy and reduced manufacturing costs.
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