Single-Use Assembly

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​PBS Biotech single-use products include:
  • Plastic bag or vessel
  • Enclosed Vertical-Wheel™ mixing mechanism
  • Connectors, tubing, sampling manifolds, and filters

Our single-use components have the follow characteristics:
  • Gamma-sterilized USP Class VI grade or equivalent plastics for all product-contact materials
  • No attached motor so the plastic vessels are not penetrated by an axle; no seal or leak issues
  • Complete tubing sets for gas/liquid reagent handling and ports for sensors and samplers
  • Customization capabilities for incorporating different types of tubing and sensors
  • Unique bag shape with perpendicular sides avoids major crease folds
  • Stainless steel housing design is perfect fit for the plastic bag; no wasted space or smushing
We have selected polyvinylidine flouride (PVDF) as our bag film material for its superior properties and performance in context of the demanding applications of the biotech industry. PVDF is a specialty plastic used in applications requiring the highest purity, strength, and resistance. It is a highly non-reactive and pure thermoplastic fluoropolymer that is chemically inert and superior in strength, resulting in ultra-low surface binding, minimal leachables and extractables, and enhanced durability. These features are not found in traditional single-use bioreactor bags and vessels. 

To maintain strict quality control and lot traceability, all PBS Biotech single-use bags and vessels are built, integrated, and 100% tested in-house within our clean room facilities.


The entire line of single-use products, including the internal Vertical-Wheel™mixer, is packaged and then exposed to 25-40 kGy sterilization dosage by gamma radiation.  The PBS MINI and PBS 3 units use a polycarbonate (PC) plastic vessel, while the PBS 15, PBS 80, and PBS 500 single use products consist of bags made of PVDF.  

All single-use vessels and bags are designed to meet a wide range of applications and to provide maximum value and cell growth.  Each product is hand-crafted with the user in mind, allowing for low profile storage, easy installation, and changing by a single operator.  The user can unpack the vessel or bag and install the unit along with tubing, filters, and sampling manifolds in a matter of minutes.

PBS Biotech single use-bioreactors are designed to be compatible with all popular reusable and single-use pH and DO probes.

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