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Single-Use Assembly

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​PBS Biotech single-use products include:
  • Plastic bag or vessel
  • Enclosed Vertical-Wheel® mixing mechanism
  • Connectors, tubing, sampling manifolds, and filters

Our single-use components have the follow characteristics:
  • Gamma-sterilized USP Class VI grade or equivalent plastics for all product-contact materials
  • No attached motor so the plastic vessels are not penetrated by an axle; no seal or leak issues
  • Complete tubing sets for gas/liquid reagent handling and ports for sensors and samplers
  • Customization capabilities for incorporating different types of tubing and sensors
  • Unique bag shape with perpendicular sides avoids major crease folds
  • Stainless steel housing design is perfect fit for the plastic bag; no wasted space or smushing
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We have selected polyvinylidine flouride (PVDF) as our bag film material for its superior properties and performance in context of the demanding applications of the biotech industry. PVDF is a specialty plastic used in applications requiring the highest purity, strength, and resistance. It is a highly non-reactive and pure thermoplastic fluoropolymer that is chemically inert and superior in strength, resulting in ultra-low surface binding, minimal leachables and extractables, and enhanced durability. These features are not found in traditional single-use bioreactor bags and vessels. 

To maintain strict quality control and lot traceability, all PBS Biotech single-use bags and vessels are built, integrated, and 100% tested in-house within our clean room facilities.

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The entire line of single-use products, including the internal Vertical-Wheel™mixer, is packaged and then exposed to 25-40 kGy sterilization dosage by gamma radiation.  The PBS MINI and PBS 3 units use a polycarbonate (PC) plastic vessel, while the PBS 15, PBS 80, and PBS 500 single use products consist of bags made of PVDF.  

All single-use vessels and bags are designed to meet a wide range of applications and to provide maximum value and cell growth.  Each product is hand-crafted with the user in mind, allowing for low profile storage, easy installation, and changing by a single operator.  The user can unpack the vessel or bag and install the unit along with tubing, filters, and sampling manifolds in a matter of minutes.

PBS Biotech single use-bioreactors are designed to be compatible with all popular reusable and single-use pH and DO probes.


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