Bioreactor System
Proven Benefits of PBS Vertical-Wheel Bioreactors:
​
​Superior Mixing Performance
  • Efficient mixing with homogeneous particle suspension and low shear stress
True Scalability
  • Can be used for process development that will have predictive performance in progressively larger Vertical-Wheel bioreactors, up to commercial scale​
Certified Plastic Components
  • Product contact materials certified to meet the requirements for USP Class VI Testing for Plastics <88> and/or ISO 10993, with complete material lot traceability
Embedded Controller
  • Intuitive and reliable control system with touchscreen interface allows for customizable, secure, and remote access control and alarm reporting
Compact Footprint
  • Compact design and small footprint, with simple setup and training requirements: plug-and-play right out of the box
  • Converts the buoyancy of air bubbles into rotational energy, with agitation speed controlled by flow rate
  • Agitation, pH, and DO control through main sparger
  • Microsparger with customizable pore size for high mass transfer rates; ​efficient CO2 stripping
  • ​Optimal for high density suspension cell culture processes including CHO, HEK293, Sf9, and MDCK
  • Magnetic coupling between Vertical-Wheel and housing unit controls agitation speed and allows for lower working volumes for in situ harvesting
  • Low shear and homogenous mixing eliminates need for anti-foaming agents or shear protectants
  • Optimal for culturing shear-sensitive cell aggregates or anchorage-dependent cells on microcarriers
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